An ill woman and her son are on a plane to New York. Awaiting them, a doctor with an array of ultramodern medical technology will give them the best chance to cure her ailment. Her plane is then, of course, hijacked. All of this is a slow build to a reveal that you can see coming from a mile off her ailment isn’t an ailment; she’s a vampire trying desperately to suppress the monster within, and the hijackers are about to find out that they aren’t in the movie they thought they were in.